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https://elib.belstu.by/handle/123456789/14683| Title: | Synthesis of (2-fluorophenyl) and (4-fluorophenyl)-(2-nitromethyl)-methanones as precursors of fluorinated prostanoids |
| Authors: | Antonevich, I. P. Katok, Ya. M. Nesterova, S. V. |
| Keywords: | фторсодержащие соединения фторсодержащие простаноиды нитросоединения первичные нитросоединения органические соединения |
| Issue Date: | 2014 |
| Publisher: | BSTU |
| Citation: | Antonevich, I. P. Synthesis of (2-fluorophenyl) and (4-fluorophenyl)-(2-nitromethyl)-methanones as precursors of fluorinated prostanoids / I. P. Antonevich, Ya. M. Katok, S. V. Nesterova // Proceedings of BSTU. No. 4. – Minsk : BSTU, 2014. – P. 70-73 |
| Abstract: | The synthesis of new fluorinated primary nitrocompounds ?(2-fluorophenyl)and (4-fluorophenyl)-(2-nitromethylcyclopentyl)methanones has been realized by the nitromethane 1,4-addition to 1-acylcyclopentenes, available by the reductive cleavage of corresponding cyclopent-5-en[d]isoxazolines. The obtained nitrocompounds are the precursors of new fluorinated prostaglandin analogues, which could be synthesized via the formation of second prostanoids side chain by nitrile oxides method. |
| URI: | https://elib.belstu.by/handle/123456789/14683 |
| Appears in Collections: | 2014, № 4 |
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