Impact of electrospinning technological parameters on chitosan nanofibers coating morphology and surface density

Abstract

Electrospinning from solutions of polymers as a perspective way of nanofibres manufacture in the field of nanotechnologies is reviewed in the paper. Chitosan which possesses a wound-healing effect is used as nanofiber-forming polymer; it is also non-toxical, biocompatible and biodegradable. Nanofibres on its basis manifest a superdeveloped surface, a nd voids rating. Taking into account curative properties, chitosan is very effective at creation ambustial, long non-healing wound and trophic ulcers. Nano-fibres from chitosan were produced according to the Nanospider technology on the NS LAB 500 S (“ELMARCO”, Czech Republic). During process of nanofibres electrospinning potencial difference be-tween electrodes up to 60 kV wa s created. Impact of electrospinni ng technological parameters on chi-tosan nanofibers coating morpholo gy and surface density are described. Most preferred electrospinning process parameters are selected. The structure of a nanofiber layer is analyzed by method of scanning microscopy on JSM-5610 LV JEOL. SEM images of nanofibres are presented. The results of work can be used on medical devices production.