Please use this identifier to cite or link to this item:
https://elib.belstu.by/handle/123456789/14372
Title: | trans-Hydroxylation of cyclopent-5-ene[d]isoxazolines |
Authors: | Antonevich, I. P. Nesterova, S. V. |
Keywords: | синтезированные вещества биологически активные соединения |
Issue Date: | 2013 |
Publisher: | BSTU |
Citation: | Antonevich, I. P. trans-Hydroxylation of cyclopent-5-ene[d]isoxazolines / I. P. Antonevich, S. V. Nesterova // Proceedings of BSTU. – Minsk : BSTU. – 2013. – № 3. – P. 91-95. |
Abstract: | The title reaction has been studied as a variant of the cyclopentane ring functionalization of cyclopent-5-ene[d]isoxazolines as the key intermediates in total synthesis of azaand oxo prostaglandin analogues by nitrileoxides approach. The oxidation, epoxides cleavage and hydrolysis of obtained monoesters and/or acylation lead with good yields to trans-5,6-dihydroxycyclopentanoisoxazolines or their acyl derivatives. The synthesized substances are the intermediates in total synthesis of prostaglandin analogues, as well as perspective biologically active compounds. |
URI: | https://elib.belstu.by/handle/123456789/14372 |
Appears in Collections: | 2013, № 4 |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.